Bioprocess development (USP & DSP)
Your partner from the start
In order to develop the product that fits your patient’s needs, Yposkesi offers upstream (USP) and downstream (DSP) processes for viral vector manufacturing. From full-scale feasibility batches in pilot labs to small-scale process evaluations and process scale-ups, we can support the initial stages of your bioprocess project such as productivity evaluation, comparison of different vector constructions and your choice of industrial processes (adherent vs. suspension processes).
Lean on our expertise
With more than 30 years of experience, Yposkesi can partner with you to develop the best manufacturing process for your gene therapy product. With experience across numerous transgenes and vector types, several solutions for adherent or suspension systems and optimized purification processes, our state-of-the-art laboratories are fully equipped to streamline the manufacturing processes.
Quality by Design Approach
Risk management being one of our main concerns, our process development always follows a Quality by Design approach.
Frequently Asked Questions (FAQs)
Bioprocess development is the process of creating a new bioprocess, which is a series of steps and reactions used to produce, analyze, or purify biological products. It is similar to pharmaceutical development, which uses living cells instead of chemical reactions to make drugs. However, it can also be used to produce food, biopolymers (such as plastics), biofuels, and many other beneficial products.
As a CDMO, bioprocess is in our core, our purpose is to reduce costs and increase the efficiency of manufacturing processes using biological organisms. We deploy proprietary data integrity and compliance solutions, while improving time to market and product reliability.
USP means Upstream process and DSP means Downstream process. USP is the development of cell culture and DSP is the purification step. Together they are the bioprocesses.
They are an important step because the development of processes that can be transposed to an industrial scale is essential to obtain a competitive product on the market.