Increasing accessibility to new gene therapies
Capacity
Time is of essence in clinical development of new therapies, and manufacturing is often a real bottleneck for gene therapy products. At Yposkesi, we have one of the largest AAV (Adeno-Associated Virus) and lentiviral vector production capacities in Europe. The sheer size of our GMP facility, dedicated manpower and expertise enable us to readily accommodate new projects and meet the on-time demands of those clients breaking ground in therapeutic treatments.
Innovation
There is a significant industrial challenge to overcome the manufacturing costs of gene therapy products. As a leading CDMO (Contract Development Manufacturing Organization), Yposkesi is at the forefront of designing new techniques that improve process robustness and scalability, thereby increasing productivity. We have a highly-skilled and dedicated innovation team focused on the evolving needs of our clients and their requirements for a committed, sustainable and competitive AAV and lentiviral vector supplier.
Integrated Services
Yposkesi provides integrated services with both technical expertise and a long-term commitment to quality. Our services encompass process development, GMP manufacturing of AAV and lentiviral vectors, Fill&Finish, QC, QA and regulatory support. We aim to establish an open and trustworthy relationship with clients with the ultimate objective of supporting them in reducing time-to-market and ensuring an uninterrupted supply of viral vectors.
About Us
Yposkesi is one of the largest Contract Development & Manufacturing Organizations (CDMO) in Europe for AAV and lentiviral vector production. A spin-off from the world-class gene therapy pioneer Genethon, Yposkesi capitalizes on more than 20 years’ expertise in biotherapeutic research to offer customers full integrated services; bioprocess development (USP & DSP), from small/pilot to large production scale, analytical development, GMP manufacturing of clinical batches of lentiviral and AAV vectors and regulatory support. Its current 50,000 sq ft (approx. 5,000m2) state-of-the-art facility designed for high efficiency houses four independent manufacturing suites for bulk drug substance and two Fill&Finish suites.
Yposkesi is extending this capacity. By 2021 it will double its global footprint to 100,000 sq ft (approx. 10,000m2) with a second large-scale facility designed for commercial production and EMA and FDA compliance. Yposkesi invests significantly in innovation and bioprocessing to deliver on high quality projects, cost-effectively.
Founded in 2016 by patient association AFM-Telethon and the SPI investment fund from Bpifrance, the state-owned French investment bank, Yposkesi, which employs over 175 industrial and technical specialists, is led by directors with an established track record in gene therapy and GMP biomanufacturing.
Bioprocess development (USP & DSP)
We use innovation to reach new heights in production efficiency.
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GMP manufacturing of clinical and commercial viral vector batches
Our extensive AAV and lentiviral vector manufacturing capacity helps ensure on-time deliver.
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Analytical development, assays qualification & validation
Our experts aim to satisfy all your analytical needs with high quality.
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Fill & Finish
We offer two options for Fill&Finish: Crystal® Closed Vial Technology or glass vials.
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Our News & Events
Yposkesi is proud to be a sponsor of the @ESGCT congress, October 22 – 25, 2019
Yposkesi thanks everyone who attended the #Mesa19 roundtable on ‘Challenges in gene therapy manufacturing.
Yposkesi to host roundtable on challenges in gene therapy manufacturing at the Cell and Gene Meeting on the Mesa, October 2-4
